EC 2 - Transferases
EC 2.3 - Acyltransferases
EC 2.3.1 - Transferring groups other than amino-acyl groups
EC 2.3.1.22 - 2-acylglycerol O-acyltransferase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.3.1.22
Names
Accepted name:
2-acylglycerol O-acyltransferase
Other
names:
acyl coenzyme A-monoglyceride acyltransferase
acylglycerol palmitoyltransferase
monoacylglycerol acyltransferase
monoglyceride acyltransferase
acylglycerol palmitoyltransferase
monoacylglycerol acyltransferase
monoglyceride acyltransferase
Systematic name:
acyl-CoA:2-acylglycerol O-acyltransferase
Reaction
- acyl-CoA + 2-acylglycerol = CoA + diacylglycerol
Comments:
Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.
Links to other databases
Gene Ontology:
GO:0003846
CAS Registry Number:
9055-17-8
References
-
Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells.Can. J. Biochem. Cell Biol. 63 : 341-347 (1985). [PMID: 4016575]
[EC 2.3.1.22 created 1972, modified 1986, modified 1989]