EC 2.3.1.22 - 2-acylglycerol O-acyltransferase

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IntEnz Enzyme Nomenclature
EC 2.3.1.22

Names

Accepted name:
2-acylglycerol O-acyltransferase
Other names:
acyl coenzyme A-monoglyceride acyltransferase
acylglycerol palmitoyltransferase
monoacylglycerol acyltransferase
monoglyceride acyltransferase
Systematic name:
acyl-CoA:2-acylglycerol O-acyltransferase

Reaction

Comments:

Various 2-acylglycerols can act as acceptor; palmitoyl-CoA and other long-chain acyl-CoAs can act as donors. The sn-1 position and the sn-3 position are both acylated, at about the same rate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003846
CAS Registry Number: 9055-17-8
UniProtKB/Swiss-Prot: (18) [show] [UniProt]

References

  1. Manganaro, F. and Kuksis, A.
    Purification and preliminary characterization of 2-monoacylglycerol acyltransferase from rat intestinal villus cells.
    Can. J. Biochem. Cell Biol. 63 : 341-347 (1985). [PMID: 4016575]

[EC 2.3.1.22 created 1972, modified 1986, modified 1989]