EC 2.3.1.219 - Demethoxycurcumin synthase

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IntEnz Enzyme Nomenclature
EC 2.3.1.219

Names

Accepted name:
demethoxycurcumin synthase
Other name:
CURS3
Systematic name:
4-coumaroyl-CoA:feruloylacetyl-CoA feruloyltransferase (demethoxycurcumin-forming)

Reactions

Comments:

A polyketide synthase from the plant Curcuma longa (turmeric). Three isoforms exist, CURS1, CURS2 and CURS3. While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate (cf. EC 2.3.1.217, curcumin synthase), CURS3 can accept 4-coumaroyl-CoA equally well [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102103 , GO:0102105
UniProtKB/Swiss-Prot:

References

  1. Katsuyama, Y., Kita, T., Horinouchi, S.
    Identification and characterization of multiple curcumin synthases from the herb Curcuma longa.
    FEBS Lett. 583: 2799-2803 (2009). [PMID: 19622354]

[EC 2.3.1.219 created 2013]