IntEnz - EC 2.3.1.210

EC 2 - Transferases

EC 2.3 - Acyltransferases

EC 2.3.1 - Transferring groups other than amino-acyl groups

EC 2.3.1.210 - DTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase

IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.3.1.210

Names

Accepted name:

dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase

Other names:

TDP-fucosamine acetyltransferase
WecD
RffC

Systematic name:

acetyl-CoA:dTDP-4-amino-4,6-dideoxy-α-D-galactose N-acetyltransferase

Reaction

34443 [IUBMB]

acetyl-CoA

acetyl-CoA

Name origin: UniProt - CHECKED (C)

CHEBI:57288

Formula: C23H34N7O17P3S
Charge: -4

ChEBI compound status: CHECKED (C)

+

dTDP-4-amino-4,6-dideoxy-α-D-galactose

dTDP-4-amino-4,6-dideoxy-alpha-D-galactose

Name origin: UniProt - CHECKED (C)

CHEBI:68492

Formula: C16H26N3O14P2
Charge: -1

ChEBI compound status: CHECKED (C)

=

CoA

CoA

Name origin: UniProt - CHECKED (C)

CHEBI:57287

Formula: C21H32N7O16P3S
Charge: -4

ChEBI compound status: CHECKED (C)

+

dTDP-4-acetamido-4,6-dideoxy-α-D-galactose

dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose

Name origin: UniProt - CHECKED (C)

CHEBI:68493

Formula: C18H27N3O15P2
Charge: -2

ChEBI compound status: CHECKED (C)

+

H⁺

H(+)

Name origin: UniProt - CHECKED (C)

CHEBI:15378

Formula: H
Charge: 1

ChEBI compound status: CHECKED (C)

Comments:

The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of Enterobacterial Common Antigen (ECA).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway

Structural data: CSA , EC2PDB

UniProtKB/Swiss-Prot:

WECD_ECOL6

WECD_ECOLI

References

Hung, M. N., Rangarajan, E., Munger, C., Nadeau, G., Sulea, T., Matte, A.

Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis.

J. Bacteriol. 188: 5606-5617 (2006). [PMID: 16855251]

[EC 2.3.1.210 created 2012]