EC 2.3.1.208 - 4-hydroxycoumarin synthase

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IntEnz Enzyme Nomenclature
EC 2.3.1.208

Names

Accepted name:
4-hydroxycoumarin synthase
Other names:
BIS2
BIS3
Systematic name:
malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase

Reaction

Comments:

The enzyme, a polyketide synthase, can also accept benzoyl-CoA as substrate, which it condenses with 3 malonyl-CoA molecules to form 3,5-dihydroxybiphenyl (cf. EC 2.3.1.177, biphenyl synthase) [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Liu, B., Raeth, T., Beuerle, T., Beerhues, L.
    A novel 4-hydroxycoumarin biosynthetic pathway.
    Plant Mol. Biol. 72 : 17-25 (2010). [PMID: 19757094]

[EC 2.3.1.208 created 2012]