EC - Lipoyl amidotransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
lipoyl amidotransferase
Other name:
LipL (gene name, ambiguous)
Systematic name:
[glycine cleavage system H]-N6-lipoyl-L-lysine:[lipoyl-carrier protein]-N6-L-lysine lipoyltransferase



In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid. The enzyme is bound to 2-oxo-acid dehydrogenases such as the pyruvate dehydrogenase complex, where it transfers the lipoyl moiety from lipoyl-[glycine cleavage system H] to the E2 subunits of the complexes.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Christensen, Q. H., Hagar, J. A., O'Riordan, M. X., Cronan, J. E.
    A complex lipoate utilization pathway in Listeria monocytogenes.
    J. Biol. Chem. 286 : 31447-31456 (2011). [PMID: 21768091]

[EC created 2012]