EC - Glycerol-3-phosphate 1-O-acyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
glycerol-3-phosphate 1-O-acyltransferase
Other names:
3-glycerophosphate acyltransferase
α-glycerophosphate acyltransferase
sn-glycerol 3-phosphate acyltransferase
sn-glycerol-3-phosphate acyltransferase
ACP:sn-glycerol-3-phosphate acyltransferase
glycerol 3-phosphate acyltransferase
glycerol phosphate acyltransferase
glycerol phosphate transacylase
glycerophosphate acyltransferase
glycerophosphate transacylase
glycerol-3-phosphate O-acyltransferase
Systematic name:
acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase



Acyl-[acyl-carrier protein] can also act as acyl donor. The enzyme acts only on derivatives of fatty acids of chain length above C10.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004366 , GO:0102420
CAS Registry Number: 9029-96-3
UniProtKB/Swiss-Prot: (226) [show] [UniProt]


  1. Bertrams, M. and Heinz, E.
    Positional specificity and fatty-acid selectivity of purified sn-glycerol 3-phosphate acyltransferases from chloroplasts.
    Plant Physiol. 68 : 653-657 (1981).
  2. Frentzen, M., Heinz, E., McKeon, T.A. and Stumpf, P.K.
    Specificities and selectivities of glycerol-3-phosphate acyltransferase and monoacylglycerol-3-phosphate acyltransferase from pea and spinach chloroplasts.
    Eur. J. Biochem. 129 : 629-636 (1983). [PMID: 6825679]
  3. Green, P.R., Merrill, A.H. and Bell, R.M.
    Membrane phospholipid synthesis in Escherichia coli. Purification, reconstitution, and characterization of sn-glycerol-3-phosphate acyltransferase.
    J. Biol. Chem. 256 : 11151-11159 (1981). [PMID: 6350296]
  4. Yamashita, S. and Numa, N.
    Partial purification and properties of glycerophosphate acyltransferase from rat liver. Formation of 1-acylglycerol 3-phosphate from sn-glycerol 3-phosphate and palmityl coenzyme A.
    Eur. J. Biochem. 31 : 565-573 (1972). [PMID: 4650158]

[EC created 1961, modified 1976, modified 1990]