EC 2.3.1.137 - Carnitine O-octanoyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.3.1.137

Names

Accepted name:
carnitine O-octanoyltransferase
Other names:
carnitine medium-chain acyltransferase
easily solubilized mitochondrial carnitine palmitoyltransferase
medium-chain/long-chain carnitine acyltransferase
overt mitochondrial carnitine palmitoyltransferase
Systematic name:
octanoyl-CoA:L-carnitine O-octanoyltransferase

Reaction

Comments:

Acts on a range of acyl-CoAs, with optimal activity with C6 or C8 acyl groups. cf. EC 2.3.1.7 (carnitine O-acetyltransferase) and EC 2.3.1.21 (carnitine O-palmitoyltransferase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008458
CAS Registry Number: 39369-19-2
UniProtKB/Swiss-Prot:

References

  1. Farrell, S.O., Fiol, C.J., Reddy, J.K. and Bieber, L.L.
    Properties of purified carnitine acyltransferases of mouse liver peroxisomes.
    J. Biol. Chem. 259: 13089-13095 (1984). [PMID: 6436243]
  2. Healy, M.J., Kerner, J. and Bieber, L.L.
    Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?
    Biochem. J. 249: 231-237 (1988). [PMID: 3342008]
  3. Miyazawa, S., Ozasa, H., Osumi, T. and Hashimoto, T.
    Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver.
    J. Biochem. (Tokyo) 94: 529-542 (1983). [PMID: 6630173]

[EC 2.3.1.137 created 1992]