EC - Formylmethanofuran—tetrahydromethanopterin N-formyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
formylmethanofuran—tetrahydromethanopterin N-formyltransferase
Other names:
N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase
formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase
formylmethanofuran:tetrahydromethanopterin formyltransferase
formylmethanofuran-tetrahydromethanopterin formyltransferase
Systematic name:
formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase



Methanofuran is a complex 4-substituted furfurylamine and is involved in the formation of methane from CO2 in Methanobacterium thermoautotrophicum.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030270
CAS Registry Number: 105669-83-8
UniProtKB/Swiss-Prot: (13) [show] [UniProt]


  1. Donnelly, M.I. and Wolfe, R.S.
    The role of formylmethanofuran: tetrahydromethanopterin formyltransferase in methanogenesis from carbon dioxide.
    J. Biol. Chem. 261 : 16653-16659 (1986). [PMID: 3097011]
  2. Leigh, J.A., Rinehart, K.L. and Wolfe, R.S.
    Structure of methanofuran, the carbon-dioxide reduction factor of Methanobacterium thermoautotrophicum.
    J. Am. Chem. Soc. 106 : 3636-3640 (1984).

[EC created 1989]