EC - Formaldehyde transketolase

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IntEnz Enzyme Nomenclature


Accepted name:
formaldehyde transketolase
Other names:
dihydroxyacetone synthase
glycerone synthase
Systematic name:
D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase




A thiamine-diphosphate protein. Not identical with EC transketolase. Also converts hydroxypyruvate and formaldehyde into glycerone and CO2.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00635
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047896


  1. Bystrykh, L.V., Sokolov, A.P. and Trotsenko, Yu.A.
    Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts.
    Dokl. Akad. Nauk S.S.S.R. 258: 499-501 (1981). [PMID: 7249920]
  2. Kato, N., Higuchi, T., Sakazawa, C., Nishizawa, T., Tani, Y. and Yamada, H.
    Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, Candida boidinii (Kloeckera sp.) No. 2201.
    Biochim. Biophys. Acta 715: 143-150 (1982). [PMID: 7074134]
  3. Waites, M.J. and Quayle, J.R.
    The interrelation between transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii.
    J. Gen. Microbiol. 124: 309-316 (1981). [PMID: 6276498]

[EC created 1984]