EC - 3-methyl-2-oxobutanoate hydroxymethyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
3-methyl-2-oxobutanoate hydroxymethyltransferase
Other names:
5,10-methylene tetrahydrofolate:α-ketoisovalerate hydroxymethyltransferase
α-ketoisovalerate hydroxymethyltransferase
dehydropantoate hydroxymethyltransferase
ketopantoate hydroxymethyltransferase
oxopantoate hydroxymethyltransferase
Systematic name:
5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003864
CAS Registry Number: 56093-17-5
UniProtKB/Swiss-Prot: (575) [show] [UniProt]


  1. Powers, S.G. and Snell, E.E.
    Ketopantoate hydroxymethyltransferase. II. Physical, catalytic, and regulatory properties.
    J. Biol. Chem. 251 : 3786-3793 (1976). [PMID: 6463]
  2. Teller, J.H., Powers, S.G. and Snell, E.E.
    Ketopantoate hydroxymethyltransferase. I. Purification and role in pantothenate biosynthesis.
    J. Biol. Chem. 251 : 3780-3785 (1976). [PMID: 776976]

[EC created 1982]