EC 2.1.1.99 - 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.99

Names

Accepted name:
3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
Other names:
16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase
NMT
16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase
S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase
Systematic name:
S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase

Reaction

Comments:

Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkle Catharanthus roseus.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030768
CAS Registry Number: 113478-40-3
UniProtKB/Swiss-Prot:

References

  1. De Luca, V., Balsevich, J., Tyler, R.T., Eilert, U., Panchuk, B.D. and Kurz, W.G.W.
    Biosynthesis of indole alkaloids - developmental regulation of the biosynthetic-pathway from tabersonine to vindoline in Catharanthus roseus.
    J. Plant Physiol. 125: 147-156 (1986).
  2. De Luca, V. and Cutler, A.J.
    Subcellular localization of enzymes involved in indole alkaloid biosynthesis in Catharanthus roseus.
    Plant Physiol. 85: 1099-1102 (1987).

[EC 2.1.1.99 created 1990, modified 2005]