EC 2.1.1.76 - Quercetin 3-O-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.76

Names

Accepted name:
quercetin 3-O-methyltransferase
Other names:
flavonoid 3-methyltransferase
flavonol 3-O-methyltransferase
Systematic name:
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase

Reaction

Comments:

Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030755
CAS Registry Number: 75603-21-3

References

  1. De Luca, V., Brunet, G., Khouri, H., Ibrahim, R. and Hrazdina, G.
    Flavonol 3-O-methyltransferase in plant-tissues.
    Z. Naturforsch. 37 : 134-135 (1982).
  2. De Luca, V. and Ibrahim, R.K.
    Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases.
    Arch. Biochem. Biophys. 238 : 596-605 (1985). [PMID: 3994393]
  3. De Luca, V. and Ibrahim, R.K.
    Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases.
    Arch. Biochem. Biophys. 238 : 606-618 (1985). [PMID: 3994394]
  4. Ibrahim, R.K. and De Luca,V.
    Polymethylated flavonol synthesis is catalyzed by distinct O-methyltransferases.
    Naturwissenschaften 69 : 41-42 (1982).

[EC 2.1.1.76 created 1984]