IntEnz

EC 2.1.1.75 - Apigenin 4'-O-methyltransferase

IntEnz Enzyme Nomenclature
EC 2.1.1.75

Names

Reaction

• 20429 [IUBMB]
  apigenin

  apigenin

  Name origin: UniProt - CHECKED (C)

  CHEBI:58470

  Formula: C15H9O5
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  S-adenosyl-L-methionine

  S-adenosyl-L-methionine

  Name origin: UniProt - CHECKED (C)

  CHEBI:59789

  Formula: C15H23N6O5S
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  =

  acacetin

  acacetin

  Name origin: UniProt - CHECKED (C)

  CHEBI:57284

  Formula: C16H11O5
  Charge: -1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  S-adenosyl-L-homocysteine

  S-adenosyl-L-homocysteine

  Name origin: UniProt - CHECKED (C)

  CHEBI:57856

  Formula: C14H20N6O5S
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

Comments:

Converts apigenin into acacetin. Naringenin (5,7,4'-trihydroxyflavanone) can also act as an acceptor, but more slowly.

Links to other databases

References

1. Kuroki, G. and Poulton, J.E.
   The para-O-methylation of apigenin to acacetin by cell-free extracts of Robinia pseudoacacia L.
   Z. Naturforsch. C: Biosci. 36: 916-920 (1981).

[EC 2.1.1.75 created 1984]