IntEnz

EC 2.1.1.60 - Calmodulin-lysine N-methyltransferase

IntEnz Enzyme Nomenclature
EC 2.1.1.60

Names

Reaction

• 21556 [IUBMB]
  [calmodulin]-L-lysine

  [calmodulin]-L-lysine

  GENERIC:11360

  Is ROOT: no
  ROOT compound: GENERIC:11359

  Number of residues: 1

  L-lysine residue L-lysine residue Name origin: UniProt - CHECKED (C) CHEBI:29969 Formula: C6H13N2O Charge: 1 Position: undefined ChEBI compound status: CHECKED (C)

  +

  S-adenosyl-L-methionine

  S-adenosyl-L-methionine

  Name origin: UniProt - CHECKED (C)

  CHEBI:59789

  Formula: C15H23N6O5S
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  =

  [calmodulin]-N⁶-methyl-L-lysine

  [calmodulin]-N(6)-methyl-L-lysine

  GENERIC:11361

  Is ROOT: no
  ROOT compound: GENERIC:11359

  Number of residues: 1

  N6-methyl-L-lysine residue N(6)-methyl-L-lysine residue Name origin: UniProt - CHECKED (C) CHEBI:61929 Formula: C7H15N2O Charge: 1 Position: undefined ChEBI compound status: CHECKED (C)

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  S-adenosyl-L-homocysteine

  S-adenosyl-L-homocysteine

  Name origin: UniProt - CHECKED (C)

  CHEBI:57856

  Formula: C14H20N6O5S
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

Comments:

One of a group of enzymes methylating proteins; see also EC 2.1.1.43 histone-lysine N-methyltransferase and EC 2.1.1.59 [cytochrome-c]-lysine N-methyltransferase.

Links to other databases

References

1. Sitaramayya, A., Wright, L.S. and Siegel, F.L.
   Enzymatic methylation of calmodulin in rat brain cytosol.
   J. Biol. Chem. 255 : 8894-8900 (1980). [PMID: 6773954]

[EC 2.1.1.60 created 1982, modified 1983]