EC 2.1.1.350 - Menaquinone C8-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.350

Names

Accepted name:
menaquinone C8-methyltransferase
Other names:
mqnK (gene name)
menK (gene name)
Systematic name:
S-adenosyl-L-methionine:menaquinone C8-methyltransferase

Reactions

Comments:

The enzyme, found in a wide range of bacteria and archaea, is a radical SAM (AdoMet) enzyme that utilizes two molecules of S-adenosyl-L-methionine, one as the methyl group donor, and one for the creation of a 5'-deoxyadenosine radical that drives the reaction forward.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Hein, S., Klimmek, O., Polly, M., Kern, M., Simon, J.
    A class C radical S-adenosylmethionine methyltransferase synthesizes 8-methylmenaquinone.
    Mol. Microbiol. 104 : 449-462 (2017). [PMID: 28164386]

[EC 2.1.1.350 created 2018]