EC 2.1.1.339 - Xanthohumol 4-O-methyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.1.1.339

Names

Accepted name:
xanthohumol 4-O-methyltransferase
Other name:
OMT2 [ambiguous]
Systematic name:
S-adenosyl-L-methionine:xanthohumol 4-O-methyltransferase

Reaction

Comments:

The enzyme from hops (Humulus lupulus) has a broad substrate specificity. The best substrates in vitro are resveratrol, desmethylxanthohumol, chalconaringenin and isoliquiritigenin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Nagel, J., Culley, L. K., Lu, Y., Liu, E., Matthews, P. D., Stevens, J. F., Page, J. E.
    EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol.
    Plant Cell 20: 186-200 (2008). [PMID: 18223037]

[EC 2.1.1.339 created 2017, modified 2018]