EC 2.1.1.339 - Xanthohumol 4-O-methyltransferase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 2.1.1.339
Names
Accepted name:
xanthohumol 4-O-methyltransferase
Other
name:
OMT2
[ambiguous]
Systematic name:
S-adenosyl-L-methionine:xanthohumol 4-O-methyltransferase
Reaction
-
51704 [IUBMB]S-adenosyl-L-methionineName origin: UniProt - CHECKED (C)Formula: C15H23N6O5S
Charge: 1ChEBI compound status: CHECKED (C)xanthohumolName origin: UniProt - CHECKED (C)Formula: C21H21O5
Charge: -1ChEBI compound status: CHECKED (C)=4-O-methylxanthohumolName origin: UniProt - CHECKED (C)Formula: C22H23O5
Charge: -1ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
The enzyme from hops (Humulus lupulus) has a broad substrate specificity. The best substrates in vitro are resveratrol, desmethylxanthohumol, chalconaringenin and isoliquiritigenin.
Links to other databases
UniProtKB/Swiss-Prot:
OMT2_HUMLU
References
-
EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol.Plant Cell 20 : 186-200 (2008). [PMID: 18223037]
[EC 2.1.1.339 created 2017, modified 2018]