EC 2.1.1.337 - Reticuline N-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.337

Names

Accepted name:
reticuline N-methyltransferase
Other name:
RNMT
Systematic name:
S-adenosyl-L-methionine:(S)-reticuline N-methyltransferase

Reactions

Comments:

The enzyme from opium poppy (Papaver somniferum) can also methylate (R)-reticuline, tetrahydropapaverine, (S)-glaucine and (S)-bulbocapnine. It is involved in the biosynthesis of the quaternary benzylisoquinoline alkaloid magnoflorine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Morris, J. S., Facchini, P. J.
    Isolation and Characterization of Reticuline N-Methyltransferase Involved in Biosynthesis of the Aporphine Alkaloid Magnoflorine in Opium Poppy.
    J. Biol. Chem. 291: 23416-23427 (2016). [PMID: 27634038]

[EC 2.1.1.337 created 2017]