EC - 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
Other names:
VTE3 (gene name)
2-methyl-6-solanyl-1,4-hydroquinone methyltransferase
MPBQ/MSBQ methyltransferase
S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C3-methyltransferase
Systematic name:
S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C-3-methyltransferase



Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102550


  1. Shintani, D. K., Cheng, Z., DellaPenna, D.
    The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.
    FEBS Lett. 511 : 1-5 (2002). [PMID: 11821038]
  2. Cheng, Z., Sattler, S., Maeda, H., Sakuragi, Y., Bryant, D. A., DellaPenna, D.
    Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.
    Plant Cell 15 : 2343-2356 (2003). [PMID: 14508009]
  3. Van Eenennaam, A. L., Lincoln, K., Durrett, T. P., Valentin, H. E., Shewmaker, C. K., Thorne, G. M., Jiang, J., Baszis, S. R., Levering, C. K., Aasen, E. D., Hao, M., Stein, J. C., Norris, S. R., Last, R. L.
    Engineering vitamin E content: from Arabidopsis mutant to soy oil.
    Plant Cell 15 : 3007-3019 (2003). [PMID: 14630966]

[EC created 2014]