EC - Indole-3-acetate O-methyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
indole-3-acetate O-methyltransferase
Other names:
IAA carboxylmethyltransferase
Systematic name:
S-adenosyl-L-methionine:(indol-3-yl)acetate O-methyltransferase




Binds Mg2+. The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. The product, methyl (indol-3-yl)acetate is inactive as hormone [2].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0103007


  1. Zubieta, C., Ross, J. R., Koscheski, P., Yang, Y., Pichersky, E., Noel, J. P.
    Structural basis for substrate recognition in the salicylic acid carboxyl methyltransferase family.
    Plant Cell 15 : 1704-1716 (2003). [PMID: 12897246]
  2. Li, L., Hou, X., Tsuge, T., Ding, M., Aoyama, T., Oka, A., Gu, H., Zhao, Y., Qu, L. J.
    The possible action mechanisms of indole-3-acetic acid methyl ester in Arabidopsis.
    Plant Cell Rep. 27 : 575-584 (2008). [PMID: 17926040]
  3. Zhao, N., Ferrer, J. L., Ross, J., Guan, J., Yang, Y., Pichersky, E., Noel, J. P., Chen, F.
    Structural, biochemical, and phylogenetic analyses suggest that indole-3-acetic acid methyltransferase is an evolutionarily ancient member of the SABATH family.
    Plant Physiol. 146 : 455-467 (2008). [PMID: 18162595]

[EC created 2013]