EC 2.1.1.261 - 4-dimethylallyltryptophan N-methyltransferase
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IntEnz Enzyme Nomenclature
EC 2.1.1.261
Names
Accepted name:
4-dimethylallyltryptophan N-methyltransferase
Other
names:
fgaMT (gene name)
easF (gene name)
easF (gene name)
Systematic name:
S-adenosyl-L-methionine:4-(3-methylbut-2-enyl)-L-tryptophan N-methyltransferase
Reaction
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34435 [IUBMB]4-(3-methylbut-2-enyl)-L-tryptophanName origin: UniProt - CHECKED (C)Formula: C16H20N2O2
Charge: 0ChEBI compound status: CHECKED (C)S-adenosyl-L-methionineName origin: UniProt - CHECKED (C)Formula: C15H23N6O5S
Charge: 1ChEBI compound status: CHECKED (C)=4-(3-methylbut-2-enyl)-L-abrineName origin: UniProt - CHECKED (C)Formula: C17H22N2O2
Charge: 0ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
The enzyme catalyses a step in the pathway leading to biosynthesis of ergot alkaloids in certain fungi.
Links to other databases
References
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Ergot alkaloid biosynthesis in Aspergillus fumigatus. Overproduction and biochemical characterization of a 4-dimethylallyltryptophan N-methyltransferase.J. Biol. Chem. 283 : 26859-26868 (2008). [PMID: 18678866]
[EC 2.1.1.261 created 2012]