EC 2.1.1.261 - 4-dimethylallyltryptophan N-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.261

Names

Accepted name:
4-dimethylallyltryptophan N-methyltransferase
Other names:
fgaMT (gene name)
easF (gene name)
Systematic name:
S-adenosyl-L-methionine:4-(3-methylbut-2-enyl)-L-tryptophan N-methyltransferase

Reaction

Comments:

The enzyme catalyses a step in the pathway leading to biosynthesis of ergot alkaloids in certain fungi.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot: (10) [show] [UniProt]

References

  1. Rigbers, O., Li, S. M.
    Ergot alkaloid biosynthesis in Aspergillus fumigatus. Overproduction and biochemical characterization of a 4-dimethylallyltryptophan N-methyltransferase.
    J. Biol. Chem. 283: 26859-26868 (2008). [PMID: 18678866]

[EC 2.1.1.261 created 2012]