EC 2.1.1.217 - TRNA (adenine22-N1)-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.217

Names

Accepted name:
tRNA (adenine22-N1)-methyltransferase
Other names:
TrmK
YqfN
Sp1610 (gene name)
tRNA: m1A22 methyltransferase
Systematic name:
S-adenosyl-L-methionine:tRNA (adenine22-N1)-methyltransferase

Reaction

Comments:

The enzyme specifically methylates adenine22 in tRNA. Formerly EC 2.1.1.36.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ta, H. M., Kim, K. K.
    Crystal structure of Streptococcus pneumoniae Sp1610, a putative tRNA methyltransferase, in complex with S-adenosyl-L-methionine.
    Protein Sci. 19: 617-624 (2010). [PMID: 20052680]
  2. Roovers, M., Kaminska, K. H., Tkaczuk, K. L., Gigot, D., Droogmans, L., Bujnicki, J. M.
    The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).
    Nucleic Acids Res. 36: 3252-3262 (2008). [PMID: 18420655]

[EC 2.1.1.217 created 1972 as EC 2.1.1.36, part-transferred 2011 to EC 2.1.1.217]