EC - Kaempferol 4'-O-methyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
kaempferol 4'-O-methyltransferase
Other names:
S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase
F 4'-OMT
Systematic name:
S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase



The enzyme acts on the hydroxy group in the 4'-position of some flavones, flavanones and isoflavones. Kaempferol, apigenin and kaempferol triglucoside are substrates, as is genistein, which reacts more slowly. Compounds with an hydroxy group in the 3' and 4' positions, such as quercetin and eriodictyol, do not act as substrates. Similar to EC, apigenin 4'-O-methyltransferase and EC, 3,7-dimethylquercetin 4'-O-methyltransferase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033803


  1. Curir, P., Lanzotti, V., Dolci, M., Dolci, P., Pasini, C. and Tollin, G.
    Purification and properties of a new S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase from carnation (Dianthus caryophyllus L.).
    Eur. J. Biochem. 270 : 3422-3431 (2003). [PMID: 12899699]

[EC created 2004]