EC 2.1.1.142 - Cycloartenol 24-C-methyltransferase

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IntEnz Enzyme Nomenclature
EC 2.1.1.142

Names

Accepted name:
cycloartenol 24-C-methyltransferase
Other name:
sterol C-methyltransferase
Systematic name:
S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase

Reaction

Comments:

S-Adenosyl-L-methionine methylates the Si face of the 24(25)-double bond with elimination of a hydrogen atom from the pro-Z methyl group at C-25.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030796

References

  1. Mangla, A.T. and Nes, W.D.
    Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition.
    Bioorg. Med. Chem. 8: 925-936 (2000). [PMID: 10882005]

[EC 2.1.1.142 created 2001, modified 2019]