EC 1.8.3.6 - Farnesylcysteine lyase

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IntEnz Enzyme Nomenclature
EC 1.8.3.6

Names

Accepted name:
farnesylcysteine lyase
Other names:
FC lyase
FCLY
Systematic name:
S-(2E,6E)-farnesyl-L-cysteine oxidase

Reaction

Cofactor

Comments:

A flavoprotein (FAD). In contrast to mammalian EC 1.8.3.5 (prenylcysteine oxidase) the farnesylcysteine lyase from Arabidopsis is specific for S-farnesyl-L-cysteine and shows no activity with S-geranylgeranyl-L-cysteine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102149
UniProtKB/Swiss-Prot:

References

  1. Huizinga, D. H., Denton, R., Koehler, K. G., Tomasello, A., Wood, L., Sen, S. E., Crowell, D. N.
    Farnesylcysteine lyase is involved in negative regulation of abscisic acid signaling in Arabidopsis.
    Mol Plant 3: 143-155 (2010). [PMID: 19969520]
  2. Crowell, D. N., Huizinga, D. H., Deem, A. K., Trobaugh, C., Denton, R., Sen, S. E.
    Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine.
    Plant J. 50: 839-847 (2007). [PMID: 17425716]

[EC 1.8.3.6 created 2011]