EC - Cystine reductase

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IntEnz Enzyme Nomenclature


Accepted name:
cystine reductase
Other names:
NADH-dependent cystine reductase
NADH2:L-cystine oxidoreductase
cystine reductase (NADH)
cystine reductase (NADH2)
Systematic name:
L-cysteine:NAD+ oxidoreductase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050456
CAS Registry Number: 9029-18-9


  1. Romano, A.H. and Nickerson, W.J.
    Cystine reductase of pea seeds and yeast.
    J. Biol. Chem. 208 : 409-416 (1954).
  2. Carroll, J.E., Kosicki, G.W. and Thibert, R.J.
    α-Substituted cystines as possible substrates for cystine reductase and L-amino acid oxidase.
    Biochim. Biophys. Acta 198 : 601-603 (1970). [PMID: 5436160]
  3. Maresca, B., Jacobson, E., Medoff, G. and Kobayashi, G.
    Cystine reductase in the dimorphic fungus Histoplasma capsulatum.
    J. Bacteriol. 135 : 987-992 (1978). [PMID: 211119]

[EC created 1961 as EC, transferred 2002 to EC]