EC 1.8.1.15 - Mycothione reductase

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IntEnz Enzyme Nomenclature
EC 1.8.1.15

Names

Accepted name:
mycothione reductase
Other name:
mycothiol-disulfide reductase
Systematic name:
mycothiol:NAD(P)+ oxidoreductase

Reactions

Cofactor

Comments:

Contains FAD. No activity with glutathione, trypanothione or coenzyme A as substrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050627
UniProtKB/Swiss-Prot:

References

  1. Patel, M.P. and Blanchard, J.S.
    Expression, purification, and characterization of Mycobacterium tuberculosis mycothione reductase.
    Biochemistry 38: 11827-11833 (1999). [PMID: 10512639]
  2. Patel, M.P. and Blanchard, J.S.
    Mycobacterium tuberculosis mycothione reductase: pH dependence of the kinetic parameters and kinetic isotope effects.
    Biochemistry 40: 5119-5126 (2001). [PMID: 11318633]

[EC 1.8.1.15 created 2002]