EC - Nitrate reductase

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IntEnz Enzyme Nomenclature


Accepted name:
nitrate reductase
Other names:
nitrate reductase (acceptor)
respiratory nitrate reductase
nitrite:(acceptor) oxidoreductase
Systematic name:
nitrite:acceptor oxidoreductase



The Pseudomonas enzyme is a cytochrome, but the enzyme from Micrococcus halodenitrificans is an iron protein containing molybdenum. Reduced benzyl viologen and other dyes bring about the reduction of nitrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00392
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008940
CAS Registry Number: 37256-45-4


  1. Nason, A.
    Nitrate reductase
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, th ed. vol. 7, Academic Press, New York, 1963, 587-607
  2. Radcliffe, B.C. and Nicholas, D.J.D.
    Some properties of a nitrate reductase from Pseudomonas denitrificans.
    Biochim. Biophys. Acta 205: 273-287 (1970). [PMID: 4316095]
  3. Rosso, J.-P., Forget, P. and Pichinoty, F.
    Les nitrate-réductases bactériennes solubilisation, purification et propriétés de l'enzyme A de Micrococcus halodenitrificans.
    Biochim. Biophys. Acta 321: 443-455 (1973). [PMID: 4762405]

[EC created 1972, modified 1976]