EC - Nitrite dismutase

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IntEnz Enzyme Nomenclature


Accepted name:
nitrite dismutase
Other names:
Prolixin S
Nitrophorin 7
Systematic name:
nitrite:nitrite oxidoreductase




Contains ferriheme b. The enzyme is one of the nitrophorins from the salivary gland of the blood-feeding insect Rhodnius prolixus. Nitric oxide produced induces vasodilation after injection. Nitrophorins 2 and 4 can also catalyse this reaction.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. He, C., Knipp, M.
    Formation of nitric oxide from nitrite by the ferriheme b protein nitrophorin 7.
    J. Am. Chem. Soc. 131: 12042-12043 (2009). [PMID: 19655755]
  2. He, C., Ogata, H., Knipp, M.
    Formation of the complex of nitrite with the ferriheme b β-barrel proteins nitrophorin 4 and nitrophorin 7.
    Biochemistry 49: 5841-5851 (2010). [PMID: 20524697]

[EC created 2011]