EC 1 - Oxidoreductases
EC 1.7 - Acting on other nitrogenous compounds as donors
EC 1.7.2 - With a cytochrome as acceptor
EC 1.7.2.2 - Nitrite reductase (cytochrome; ammonia-forming)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.7.2.2
Names
Accepted name:
nitrite reductase (cytochrome; ammonia-forming)
Other
names:
cytochrome c nitrite reductase
multiheme nitrite reductase
multiheme nitrite reductase
Systematic name:
ammonia:ferricytochrome-c oxidoreductase
Reaction
- NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+
Cofactors
Comments:
Found as a multiheme cytochrome in many bacteria. The enzyme from Escherichia coli contains five hemes c and requires Ca2+. It also reduces nitric oxide and hydroxylamine to ammonia, and sulfite to sulfide.
Links to other databases
Gene Ontology:
GO:0042279
References
-
Structure of cytochrome c nitrite reductase.Nature 400 : 476-480 (1999). [PMID: 10440380]
[EC 1.7.2.2 created 2001]