EC 1.7.1.16 - Nitrobenzene nitroreductase

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IntEnz Enzyme Nomenclature
EC 1.7.1.16

Names

Accepted name:
nitrobenzene nitroreductase
Other name:
cnbA (gene name)
Systematic name:
N-phenylhydroxylamine:NADP+ oxidoreductase

Reaction

Cofactor

Comments:

Contains FMN. The enzyme, characterized from Pseudomonas species, catalyses two successive reductions of nitrobenzene, via a nitrosobenzene intermediate. It is also active on 1-chloro-4-nitrobenzene.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Somerville, C. C., Nishino, S. F., Spain, J. C.
    Purification and characterization of nitrobenzene nitroreductase from Pseudomonas pseudoalcaligenes JS45.
    J. Bacteriol. 177: 3837-3842 (1995). [PMID: 7601851]
  2. Wu, J. F., Jiang, C. Y., Wang, B. J., Ma, Y. F., Liu, Z. P., Liu, S. J.
    Novel partial reductive pathway for 4-chloronitrobenzene and nitrobenzene degradation in Comamonas sp. strain CNB-1.
    Appl. Environ. Microbiol. 72: 1759-1765 (2006). [PMID: 16517619]

[EC 1.7.1.16 created 2017]