EC 1.7.1.12 - N-hydroxy-2-acetamidofluorene reductase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.7.1.12

Names

Accepted name:
N-hydroxy-2-acetamidofluorene reductase
Other names:
N-hydroxy-2-acetylaminofluorene reductase
NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase
Systematic name:
2-acetamidofluorene:NAD(P)+ oxidoreductase

Reactions

Comments:

Also acts, more slowly, on N-hydroxy-4-acetamidobiphenyl.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047137
CAS Registry Number: 99890-08-1

References

  1. Gutmann, H.R. and Erickson, R.R.
    The conversion of the carcinogen N-hydroxy-2-fluorenylacetamide to o-amidophenols by rat liver in vitro. An inducible enzymatic reaction.
    J. Biol. Chem. 244: 1729-1740 (1969). [PMID: 5780838]
  2. Kitamura, S. and Tatsumi, K.
    Purification of N-hydroxy-2-acetylaminofluorene reductase from rabbit liver cytosol.
    Biochem. Biophys. Res. Commun. 133: 67-74 (1985). [PMID: 4074379]

[EC 1.7.1.12 created 1989 as EC 1.6.6.13, transferred 2002 to EC 1.7.1.12]