EC 188.8.131.52 - Demethylphylloquinone reductase
IntEnz Enzyme Nomenclature
NDC1 (gene name)
- demethylphylloquinone + NADPH + H+ = demethylphylloquinol + NADP+
The enzyme, found in plants and cyanobacteria, is involved in the biosynthesis of phylloquinone (vitamin K1), an electron carrier associated with photosystem I. The enzyme is a type II NADPH dehydrogenase and requires a flavine adenine dinucleotide cofactor.
Links to other databases
A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis.Plant Cell 27 : 1730-1741 (2015). [PMID: 26023160]
[EC 184.108.40.206 created 2015]