EC 1.6.5.12 - Demethylphylloquinone reductase

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IntEnz Enzyme Nomenclature
EC 1.6.5.12

Names

Accepted name:
demethylphylloquinone reductase
Other names:
ndbB (gene name)
NDC1 (gene name)
demethylphylloquinone:NADPH oxidoreductase
Systematic name:
NADPH:demethylphylloquinone oxidoreductase

Reaction

Cofactor

Comments:

The enzyme, found in plants and cyanobacteria, is involved in the biosynthesis of phylloquinone (vitamin K1), an electron carrier associated with photosystem I. The enzyme is a type II NADPH dehydrogenase and requires a flavine adenine dinucleotide cofactor.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Fatihi, A., Latimer, S., Schmollinger, S., Block, A., Dussault, P. H., Vermaas, W. F., Merchant, S. S., Basset, G. J.
    A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis.
    Plant Cell 27 : 1730-1741 (2015). [PMID: 26023160]

[EC 1.6.5.12 created 2015]