EC - Cytochrome-b5 reductase

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IntEnz Enzyme Nomenclature


Accepted name:
cytochrome-b5 reductase
Other names:
NADH 5α-reductase
NADH-cytochrome b5 reductase
NADH-cytochrome-b5 reductase
NADH-ferricytochrome b5 oxidoreductase
cytochrome b5 reductase
dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase
reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase
Systematic name:
NADH:ferricytochrome-b5 oxidoreductase




A flavoprotein (FAD).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004128
CAS Registry Number: 9032-25-1
UniProtKB/Swiss-Prot: (105) [show] [UniProt]


  1. Mahler, H.R., Raw, I., Molinari, R. and do Amaral, D.F.
    Studies of electron transport enzymes. II. Isolation and some properties of a cytochrome-specific reduced diphosphopyridine nucleotide dehydrogenase from pig liver.
    J. Biol. Chem. 233 : 230-239 (1958). [PMID: 13563476]
  2. Strittmatter, P.
    Microsomal cytochrome b5 and cytochrome b5 reductase.
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes , 2nd ed. vol. 8 , Academic Press , New York , 1963 , 113-145
  3. Strittmatter, P. and Velick, S.F.
    The purification and properties of microsomal cytochrome reductase.
    J. Biol. Chem. 228 : 785-799 (1957). [PMID: 13475360]

[EC created 1961]