EC - NAD(P)+ transhydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
NAD(P)+ transhydrogenase
Other names:
pyridine nucleotide transhydrogenase
transhydrogenase [ambiguous]
nicotinamide adenine dinucleotide (phosphate) transhydrogenase [ambiguous]
NAD+ transhydrogenase [ambiguous]
NADH transhydrogenase [misleading]
nicotinamide nucleotide transhydrogenase [ambiguous]
NADPH-NAD+ transhydrogenase [ambiguous]
pyridine nucleotide transferase [ambiguous]
NADPH-NAD+ oxidoreductase [ambiguous]
NADH-NADP+-transhydrogenase [ambiguous]
NADPH:NAD+ transhydrogenase
H+-Thase [ambiguous]
non-energy-linked transhydrogenase [ambiguous]
Systematic name:
NADPH:NAD+ oxidoreductase



The enzyme catalyses the NADPH-driven reduction of NAD+. This entry stands for enzymes whose stereo-specificity with respect to NADPH is not known. [cf. EC, NAD(P)+ transhydrogenase (Si-specific) and EC NAD(P)+ transhydrogenase (Re/Si-specific)].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Keister, D.L., San Pietro, A., Stolzenbach, F.E.
    Pyridine nucleotide transhydrogenase from spinach. I. Purification and properties.
    J. Biol. Chem. 235 : 2989-2996 (1960). [PMID: 13752224]

[EC created 2013]