EC - Spermidine dehydrogenase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature


Accepted name:
spermidine dehydrogenase
Other name:
spermidine:(acceptor) oxidoreductase
Systematic name:
spermidine:acceptor oxidoreductase




A flavohemoprotein (FAD). Ferricyanide, 2,6-dichloroindophenol and cytochrome c can act as acceptor. 4-Aminobutanal condenses non-enzymically to 1-pyrroline.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050289
CAS Registry Number: 9076-64-6


  1. Tabor, C.W. and Kellogg, P.D.
    Identification of flavin adenine dinucleotide and heme in a homogeneous spermidine dehydrogenase from Serratia marcescens.
    J. Biol. Chem. 245 : 5424-5433 (1970).
  2. Tabor, H. and Tabor, C.W.
    Biosynthesis and metabolism of 1,4-diaminobutane, spermidine, spermine, and related amines. IIE2a Speridine dehydrogenase.
    Adv. Enzymol. Relat. Areas Mol. Biol. 36 : 225-226 (1972).

[EC created 1976]