EC 1.5.3.19 - 4-methylaminobutanoate oxidase (formaldehyde-forming)

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IntEnz Enzyme Nomenclature
EC 1.5.3.19

Names

Accepted name:
4-methylaminobutanoate oxidase (formaldehyde-forming)
Other name:
mabO (gene name)
Systematic name:
4-methylaminobutanoate:oxygen oxidoreductase (formaldehyde-forming)

Reaction

Cofactor

Comments:

A flavoprotein (FAD). In the enzyme from the soil bacterium Arthrobacter nicotinovorans the cofactor is covalently bound. Participates in the nicotine degradation pathway of this organism.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102317
UniProtKB/Swiss-Prot:

References

  1. Chiribau, C. B., Sandu, C., Fraaije, M., Schiltz, E., Brandsch, R.
    A novel gamma-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1.
    Eur. J. Biochem. 271 : 4677-4684 (2004). [PMID: 15606755]

[EC 1.5.3.19 created 2012]