EC - FAD reductase [NAD(P)H]

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IntEnz Enzyme Nomenclature


Accepted name:
FAD reductase [NAD(P)H]
Other name:
GTNG_3158 (gene name)
Systematic name:
FADH2:NAD(P)+ oxidoreductase



This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation. The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and EC, anthranilate 3-monooxygenase (FAD). It can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD. The enzyme has a slight preference for NADPH as acceptor. cf. EC, FAD reductase (NADH).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Liu, X., Dong, Y., Li, X., Ren, Y., Li, Y., Wang, W., Wang, L., Feng, L.
    Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2.
    Microbiology (Reading, Engl.) 156 : 589-595 (2010). [PMID: 19942660]

[EC created 2012]