EC - FMN reductase [NAD(P)H]

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IntEnz Enzyme Nomenclature


Accepted name:
FMN reductase [NAD(P)H]
Other name:
Systematic name:
FMNH2:NAD(P)+ oxidoreductase




Contains FMN [3]. The enzyme can utilize NADH and NADPH with similar reaction rates. Different from EC, FMN reductase (NADH) and EC, FMN reductase (NADPH). The luminescent bacterium Vibrio harveyi possesses all three enzymes [2], while the bacterium Aliivibrio fischeri contains only this non-specific type [3]. Also reduces riboflavin and FAD, but more slowly.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0052874 , GO:0052873 , GO:0008752


  1. Tu, S. C., Becvar, J. E., Hastings, J. W.
    Kinetic studies on the mechanism of bacterial NAD(P)H:flavin oxidoreductase.
    Arch. Biochem. Biophys. 193 : 110-116 (1979). [PMID: 222213]
  2. Watanabe, H., Hastings, J. W.
    Specificities and properties of three reduced pyridine nucleotide-flavin mononucleotide reductases coupling to bacterial luciferase.
    Mol. Cell. Biochem. 44 : 181-187 (1982). [PMID: 6981058]
  3. Tang, C. K., Jeffers, C. E., Nichols, J. C., Tu, S. C.
    Flavin specificity and subunit interaction of Vibrio fischeri general NAD(P)H-flavin oxidoreductase FRG/FRase I.
    Arch. Biochem. Biophys. 392 : 110-116 (2001). [PMID: 11469801]

[EC created 2011]