EC 220.127.116.11 - Flavin reductase (NADH)
IntEnz Enzyme Nomenclature
- reduced flavin + NAD+ = flavin + NADH + H+
The enzyme from Escherichia coli W catalyses the reduction of free flavins by NADH. The enzyme has similar affinity to FAD, FMN and riboflavin. Activity with NADPH is more than 2 orders of magnitude lower than activity with NADH.
Links to other databases
Functional analysis of the small component of the 4-hydroxyphenylacetate 3-monooxygenase of Escherichia coli W: a prototype of a new flavin:NAD(P)H reductase subfamily.J. Bacteriol. 182 : 627-636 (2000). [PMID: 10633095]
[EC 18.104.22.168 created 2011]