EC 1 - Oxidoreductases
EC 1.5 - Acting on the CH-NH group of donors
EC 1.5.1 - With NAD+ or NADP+ as acceptor
EC 1.5.1.36 - Flavin reductase (NADH)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.5.1.36
Names
Accepted name:
flavin reductase (NADH)
Other
names:
NADH-dependent flavin reductase
flavin:NADH oxidoreductase
flavin:NADH oxidoreductase
Systematic name:
flavin:NAD+ oxidoreductase
Reaction
- reduced flavin + NAD+ = flavin + NADH + H+
Comments:
The enzyme from Escherichia coli W catalyses the reduction of free flavins by NADH. The enzyme has similar affinity to FAD, FMN and riboflavin. Activity with NADPH is more than 2 orders of magnitude lower than activity with NADH.
Links to other databases
Gene Ontology:
GO:0036382
References
-
Functional analysis of the small component of the 4-hydroxyphenylacetate 3-monooxygenase of Escherichia coli W: a prototype of a new flavin:NAD(P)H reductase subfamily.J. Bacteriol. 182 : 627-636 (2000). [PMID: 10633095]
[EC 1.5.1.36 created 2011]