EC 1.5.1.27 - 1,2-dehydroreticulinium reductase (NADPH)

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 1.5.1.27

Names

Accepted name:
1,2-dehydroreticulinium reductase (NADPH)
Other name:
1,2-dehydroreticulinium ion reductase
Systematic name:
(R)-reticuline:NADP+ oxidoreductase

Reaction

Comments:

Reduces the 1,2-dehydroreticulinium ion to (R)-reticuline, which is a direct precursor of morphinan alkaloids in the poppy plant. The enzyme does not catalyse the reverse reaction to any significant extent under physiological conditions.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047128
CAS Registry Number: 130590-58-8
UniProtKB/Swiss-Prot:

References

  1. De-Eknamkul, W. and Zenk, M.H.
    Purification and properties of 1,2-dehydroreticulinium reductase from Papaver somniferum seedlings.
    Phytochemistry 31: 813-821 (1992).

[EC 1.5.1.27 created 1999, modified 2004]