EC 1.5.1.18 - Ephedrine dehydrogenase

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IntEnz Enzyme Nomenclature
EC 1.5.1.18

Names

Accepted name:
ephedrine dehydrogenase
Systematic name:
(−)-ephedrine:NAD+ 2-oxidoreductase

Reaction

Comments:

The product immediately hydrolyses to methylamine and 1-hydroxy-1-phenylpropan-2-one. Acts on a number of related compounds including (−)-sympatol, (+)-pseudoephedrine and (+)-norephedrine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047877
CAS Registry Number: 73508-06-2

References

  1. Klamann, E. and Lingens, F.
    Degradation of (−)-ephedrine by Pseudomonas putida. Detection of (−)-ephedrine: NAD+-oxidoreductase from Arthrobacter globiformis.
    Z. Naturforsch. C: Biosci. 35: 80-87 (1980). [PMID: 7405363]

[EC 1.5.1.18 created 1984]