EC - Methylenetetrahydrofolate dehydrogenase (NAD+)

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IntEnz Enzyme Nomenclature


Accepted name:
methylenetetrahydrofolate dehydrogenase (NAD+)
Systematic name:
5,10-methylenetetrahydrofolate:NAD+ oxidoreductase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00616
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004487
CAS Registry Number: 82062-90-6
UniProtKB/Swiss-Prot: (19) [show] [UniProt]


  1. Moore, M.R., O'Brien, W.E. and Ljungdahl, L.G.
    Purification and characterization of nicotinamide adenine dinucleotide-dependent methylenetetrahydrofolate dehydrogenase from Clostridium formicoaceticum.
    J. Biol. Chem. 249 : 5250-5253 (1974). [PMID: 4153026]

[EC created 1978]