EC - Saccharopine dehydrogenase (NADP+, L-glutamate-forming)

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IntEnz Enzyme Nomenclature


Accepted name:
saccharopine dehydrogenase (NADP+, L-glutamate-forming)
Other names:
ε-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)
aminoadipate semialdehyde-glutamate reductase
aminoadipic semialdehyde-glutamate reductase
aminoadipic semialdehyde-glutamic reductase
saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase
saccharopine reductase
6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)
Systematic name:
N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004755
CAS Registry Number: 9033-55-0


  1. Jones, E.E. and Broquist, H.P.
    Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. 3. Aminoadipic semialdehyde-glutamate reductase.
    J. Biol. Chem. 241: 3430-3434 (1966). [PMID: 4380448]

[EC created 1972, modified 2011]