EC 1.4.9.2 - Aralkylamine dehydrogenase (azurin)

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IntEnz Enzyme Nomenclature
EC 1.4.9.2

Names

Accepted name:
aralkylamine dehydrogenase (azurin)
Other names:
aromatic amine dehydrogenase
dehydrogenase, arylamine
tyramine dehydrogenase
aralkylamine:(acceptor) oxidoreductase (deaminating)
arylamine dehydrogenase
Systematic name:
aralkylamine:azurin oxidoreductase (deaminating)

Reaction

Comments:

Phenazine methosulfate can act as acceptor. Acts on aromatic amines and, more slowly, on some long-chain aliphatic amines, but not on methylamine or ethylamine.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030059
CAS Registry Number: 85030-73-5
UniProtKB/Swiss-Prot:

References

  1. Iwaki, M., Yagi, T., Horiike, K., Saeki, Y., Ushijima, T. and Nozaki, M.
    Crystallization and properties of aromatic amine dehydrogenase from Pseudomonas sp.
    Arch. Biochem. Biophys. 220: 253-262 (1983). [PMID: 6830237]
  2. Hyun, Y. L., Davidson, V. L.
    Electron transfer reactions between aromatic amine dehydrogenase and azurin.
    Biochemistry 34: 12249-12254 (1995). [PMID: 7547967]
  3. Hyun, Y. L., Zhu, Z., Davidson, V. L.
    Gated and ungated electron transfer reactions from aromatic amine dehydrogenase to azurin.
    J. Biol. Chem. 274: 29081-29086 (1999). [PMID: 10506161]
  4. Davidson, V. L.
    Electron transfer in quinoproteins.
    Arch. Biochem. Biophys. 428: 32-40 (2004). [PMID: 15234267]
  5. Sukumar, N., Chen, Z. W., Ferrari, D., Merli, A., Rossi, G. L., Bellamy, H. D., Chistoserdov, A., Davidson, V. L., Mathews, F. S.
    Crystal structure of an electron transfer complex between aromatic amine dehydrogenase and azurin from Alcaligenes faecalis.
    Biochemistry 45: 13500-13510 (2006). [PMID: 17087503]

[EC 1.4.9.2 created 1986 as EC 1.4.99.4, transferred 2011 to 1.4.9.2]