EC 1 - Oxidoreductases
EC 1.4 - Acting on the CH-NH2 group of donors
EC 1.4.3 - With oxygen as acceptor
EC 1.4.3.15 - D-glutamate(D-aspartate) oxidase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.4.3.15
Names
Accepted name:
D-glutamate(D-aspartate) oxidase
Other
names:
D-glutamic-aspartic oxidase
D-monoaminodicarboxylic acid oxidase
D-monoaminodicarboxylic acid oxidase
Systematic name:
D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)
Reactions
- (1) D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2
- (2) D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2
Cofactor
Comments:
A flavoprotein (FAD). D-Glutamate and D-aspartate are oxidized at the same rate. Other D-monoaminodicarboxylates, and other D- and L-amino acids, are not oxidized. cf. EC 1.4.3.7, D-glutamate oxidase and EC 1.4.3.1, D-aspartate oxidase.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0047819
References
-
Purified D-glutamic-aspartic oxidase of Aspergillus ustus.J. Gen. Appl. Microbiol. 3 : 233-239 (1957).
[EC 1.4.3.15 created 1983, modified 2012]