EC 1.3.99.31 - Phytoene desaturase (lycopene-forming)

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IntEnz Enzyme Nomenclature
EC 1.3.99.31

Names

Accepted name:
phytoene desaturase (lycopene-forming)
Other names:
4-step phytoene desaturase
four-step phytoene desaturase
phytoene desaturase [ambiguous]
CrtI [ambiguous]
Systematic name:
15-cis-phytoene:acceptor oxidoreductase (lycopene-forming)

Reaction

Cofactor

Comments:

Requires FAD. The enzyme is involved in carotenoid biosynthesis and catalyses up to four desaturation steps (cf. EC 1.3.99.28 [phytoene desaturase (neurosporene-forming)], EC 1.3.99.29 [phytoene desaturase (ζ-carotene-forming)] and EC 1.3.99.30 [phytoene desaturase (3,4-didehydrolycopene-forming)]).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Fraser, P. D., Misawa, N., Linden, H., Yamano, S., Kobayashi, K., Sandmann, G.
    Expression in Escherichia coli, purification, and reactivation of the recombinant Erwinia uredovora phytoene desaturase.
    J. Biol. Chem. 267: 19891-19895 (1992). [PMID: 1400305]

[EC 1.3.99.31 created 2011]