EC 1.3.99.19 - Quinoline-4-carboxylate 2-oxidoreductase

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IntEnz Enzyme Nomenclature
EC 1.3.99.19

Names

Accepted name:
quinoline-4-carboxylate 2-oxidoreductase
Other names:
quinaldic acid 4-oxidoreductase
quinoline-4-carboxylic acid 2-oxidoreductase
Systematic name:
quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating)

Reaction

Cofactors

Comments:

A molybdenum—iron—sulfur flavoprotein with molybdopterin cytosine dinucleotide as the molybdenum cofactor. Quinoline, 4-methylquinoline and 4-chloroquinoline can also serve as substrates for the enzyme from Agrobacterium sp. 1B. Iodonitrotetrazolium chloride, thionine, menadione and 2,6-dichlorophenolindophenol can act as electron acceptors.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047123
CAS Registry Number: 175780-18-4

References

  1. Bauer, G. and Lingens, F.
    Microbial metabolism of quinoline and related compounds. XV. Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium spec.1B: a molybdenum-containing enzyme.
    Biol. Chem. Hoppe-Seyler 373: 699-705 (1992). [PMID: 1418685]

[EC 1.3.99.19 created 1999, modified 2006]