EC - 2-methylacyl-CoA dehydrogenase

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IntEnz Enzyme Nomenclature


Accepted name:
2-methylacyl-CoA dehydrogenase
Other names:
2-methyl branched chain acyl-CoA dehydrogenase
branched-chain acyl-CoA dehydrogenase
2-methylbutanoyl-CoA:(acceptor) oxidoreductase
Systematic name:
2-methylbutanoyl-CoA:acceptor oxidoreductase




Also oxidizes 2-methylpropanoyl-CoA. Not identical with EC (butyryl-CoA dehydrogenase), EC (medium-chain acyl-CoA dehydrogenase), EC (long-chain acyl-CoA dehydrogenase) or EC (very-long-chain acyl-CoA dehydrogenase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00070
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003853
CAS Registry Number: 85130-32-1


  1. Ikeda, Y., Dabrowski, C. and Tanaka, K.
    Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase.
    J. Biol. Chem. 258 : 1066-1076 (1983). [PMID: 6401712]

[EC created 1986]