EC 1 - Oxidoreductases
EC 1.3 - Acting on the CH-CH group of donors
EC 1.3.99 - With other acceptors
EC 1.3.99.12 - 2-methylacyl-CoA dehydrogenase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.3.99.12
Names
Accepted name:
2-methylacyl-CoA dehydrogenase
Other
names:
2-methyl branched chain acyl-CoA dehydrogenase
branched-chain acyl-CoA dehydrogenase
2-methylbutanoyl-CoA:(acceptor) oxidoreductase
branched-chain acyl-CoA dehydrogenase
2-methylbutanoyl-CoA:(acceptor) oxidoreductase
Systematic name:
2-methylbutanoyl-CoA:acceptor oxidoreductase
Reaction
- 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor
Cofactor
Comments:
Also oxidizes 2-methylpropanoyl-CoA. Not identical with EC 1.3.8.1 (butyryl-CoA dehydrogenase), EC 1.3.8.7 (medium-chain acyl-CoA dehydrogenase), EC 1.3.8.8 (long-chain acyl-CoA dehydrogenase) or EC 1.3.8.9 (very-long-chain acyl-CoA dehydrogenase).
Links to other databases
Protein domains and families:
PROSITE:PDOC00070
Gene Ontology:
GO:0003853
CAS Registry Number:
85130-32-1
References
-
Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase.J. Biol. Chem. 258 : 1066-1076 (1983). [PMID: 6401712]
[EC 1.3.99.12 created 1986]