EC 1.3.8.5 - 2-methyl-branched-chain-enoyl-CoA reductase

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IntEnz Enzyme Nomenclature
EC 1.3.8.5

Names

Accepted name:
2-methyl-branched-chain-enoyl-CoA reductase
Systematic name:
2-methyl-branched-chain-acyl-CoA:electron-transfer flavoprotein 2-oxidoreductase

Reaction

Cofactor

Comments:

A flavoprotein (FAD) from Ascaris suum. The enzyme functions in shuttling reducing power from the electron-transport chain to 2-methyl branched-chain enoyl CoA.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Komuniecki, R., Fekete, S. and Thissen-Parra, J.
    Purification and characterization of the 2-methyl branched-chain acyl-CoA dehydrogenase, an enzyme involved in NADH-dependent enoyl-CoA reduction in anaerobic mitochondria of the nematode, Ascaris suum.
    J. Biol. Chem. 260: 4770-4777 (1985). [PMID: 3988734]
  2. Komuniecki, R., McCrury, J., Thissen, J. and Rubin, N.
    Electron-transfer flavoprotein from anaerobic Ascaris suum mitochondria and its role in NADH-dependent 2-methyl branched-chain enoyl-CoA reduction.
    Biochim. Biophys. Acta 975: 127-131 (1989). [PMID: 2736251]

[EC 1.3.8.5 created 1992 as EC 1.3.1.52, transferred 2012 to EC 1.3.8.5]