EC 1.3.3.13 - Albonoursin synthase

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IntEnz Enzyme Nomenclature
EC 1.3.3.13

Names

Accepted name:
albonoursin synthase
Other names:
cyclo(dipeptide):oxygen oxidoreductase
cyclic dipeptide oxidase
AlbA
Systematic name:
cyclo(L-leucyl-L-phenylalanyl):oxygen oxidoreductase

Reaction

Cofactor

Comments:

A flavoprotein from the bacterium Streptomyces noursei. The enzyme can also oxidize several other cyclo dipeptides, the best being cyclo(L-tryptophyl-L-tryptophyl) and cyclo(L-phenylalanyl-L-phenylalanyl) [1,2].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Gondry, M., Lautru, S., Fusai, G., Meunier, G., Menez, A., Genet, R.
    Cyclic dipeptide oxidase from Streptomyces noursei. Isolation, purification and partial characterization of a novel, amino acyl alpha,beta-dehydrogenase.
    Eur. J. Biochem. 268: 1712-1721 (2001). [PMID: 11248691]
  2. Lautru, S., Gondry, M., Genet, R., Pernodet, J. L.
    The albonoursin gene Cluster of S noursei biosynthesis of diketopiperazine metabolites independent of nonribosomal peptide synthetases.
    Chem. Biol. 9: 1355-1364 (2002). [PMID: 12498889]

[EC 1.3.3.13 created 2013]